Congenital mitral valve anomalies in transposition of the great arteries.

Congenital mitral valve disease in transposition of the great arteries.

A spectrum of mitral valve disease was noted in 71 per cent of 163 specimens with transposition of the great arteries. At one end of the spectrum were hearts with normal mitral valve, except that the free margin of the anterior leaflet was shortened; at the other end were specimens with underdevelopment of the space between or behind the papillary muscles of the left ventricle. In additional ...

Cleft mitral valve or levo-transposition of great vessels?

A 39-year-old man was referred for echocardiography because of dyspnoea, chest pain and murmur. Main finding was a globular morphology of left ventricle with apical hypertrophy and a seemingly cleft mitral valve with mild mitral regurgitation. Trans-oesophageal echocardiography confirmed the ventricular hypertrophy and regurgitation but showed the aortic valve to lie anteriorly and to the left ...

Transposition of the great arteries

Transposition of the great arteries (TGA), also referred to as complete transposition, is a congenital cardiac malformation characterised by atrioventricular concordance and ventriculoarterial (VA) discordance. The incidence is estimated at 1 in 3,500-5,000 live births, with a male-to-female ratio 1.5 to 3.2:1. In 50% of cases, the VA discordance is an isolated finding. In 10% of cases, TGA is ...

Transposition of the great arteries.

Many patients with ventriculoarterial discordance have survived to adulthood. Those with complete transposition of the great arteries have often had an atrial switch procedure (Mustard or Senning operation) performed, which leaves the morphological right ventricle (RV) supporting the systemic circulation. RV failure and tricuspid regurgitation are common. Some patients may ultimately require ca...

Transposition of the great arteries.